Modeling anti-CD19 CAR T cell therapy in humanized mice with human immunity and autologous leukemiaResearch in context

Background: Adoptive immunotherapy using T cells expressing chimeric antigen receptors (CARs) Swivel Rocker Recliner targeting CD19 has produced remarkable clinical outcomes.However, much of the mechanisms of action, such as the development of memory responses and sources of immune cytokines, remain elusive largely due to the challenge of character

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The time-frequency analysis of the acoustic signal produced in underwater discharges based on Variational Mode Decomposition and Hilbert–Huang Transform

Abstract The experiments of underwater discharges in an anechoic pool were carried out and analysis of the time-frequency characteristics of the acoustic signals was conducted based on Variational Mode Decomposition and Hilbert–Huang Transform (VMD-HHT).We propose a relative center frequency difference method to determine the decomposition number

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Antagonistic activity of the native strain of Pseudomonas chlororaphis 3 of the Belgorod region against the bacterium of the genus Ralstonia

The paper presents data on the evaluation of the antagonistic potential of Pseudomonas chlororaphis 3 and P.chlororaphis BS-1393 strains against the bacterium of the genus Sandals Ralstonia.It was revealed that the native strain Brim Hats is 30% more effective than the collection one.A scheme for obtaining an ethyl acetate extract of phenazine comp

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